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One-step data storage in cellular DNA

The cumbersome encoding of digital data to cellular DNA hinders the use of cells as living hard drives. A new approach transfers digital information directly into cellular DNA by converting electrical signals into stable and interpretable changes in the genomes of bacterial populations.

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Fig. 1: DRIVES for direct digital-to-biological data storage.


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Correspondence to Seth L. Shipman.

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Bhattarai-Kline, S., Lear, S.K. & Shipman, S.L. One-step data storage in cellular DNA. Nat Chem Biol 17, 232–233 (2021).

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