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PROTEIN SELF-ASSEMBLY

Living cells as test tubes

Thermodynamic principles are used to map the phase behavior of a tunable protein-binding system under crowded cellular conditions. This study marks a substantial step forward in relating molecular interactions to material properties and cellular processes involving protein self-assembly.

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Fig. 1: Studying self-assembly of well-defined protein binding systems using a unified toolset.

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Correspondence to Jeetain Mittal.

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Mammen Regy, R., Mittal, J. Living cells as test tubes. Nat Chem Biol 16, 934–935 (2020). https://doi.org/10.1038/s41589-020-0615-9

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