Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.
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Zhao, H., Kwok, C.K. Bringing distant DNA together. Nat Chem Biol 17, 125–126 (2021). https://doi.org/10.1038/s41589-020-00705-2