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GENE REGULATION

Bringing distant DNA together

Nature Chemical Biology volume 17, pages 125–126 (2021)Cite this article

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Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.

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Fig. 1: Novel interaction of YY1 and G4 mediates DNA looping and gene expression.

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Author information

Authors and Affiliations

  1. Department of Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China

    Haizhou Zhao & Chun Kit Kwok

  2. State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China

    Chun Kit Kwok

  3. Shenzhen Research Institute of City University of Hong Kong, Shenzhen, China

    Chun Kit Kwok

Authors
  1. Haizhou Zhao
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  2. Chun Kit Kwok
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Correspondence to Chun Kit Kwok.

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The authors declare no competing interests.

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Zhao, H., Kwok, C.K. Bringing distant DNA together. Nat Chem Biol 17, 125–126 (2021). https://doi.org/10.1038/s41589-020-00705-2

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