Asymmetric cell division, which generates daughter cells with distinct characteristics, is a mechanism for creating complex systems through cellular differentiation. Two studies in this issue develop synthetic platforms that program spatial localization of genetic material or signaling molecules to enable asymmetric cell division in Escherichia coli.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Mushnikov, N.V., Fomicheva, A., Gomelsky, M. & Bowman, G.R. Nat. Chem. Biol. https://doi.org/10.1038/s41589-019-0340-4 (2019).
Molinari, S. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-019-0339-x (2019).
Inaba, M. & Yamashita, Y. M. Cell Stem Cell 11, 461–469 (2012).
Gardner, T. S., Cantor, C. R. & Collins, J. J. Nature 403, 339–342 (2000).
Bi, E. F. & Lutkenhaus, J. Nature 354, 161–164 (1991).
Simon, J.R., Eghtesadi, S.A., Dzuricky, M., You, L. & Chilkoti, A. Mol. Cell https://doi.org/10.1016/j.molcel.2019.05.010 (2019).
Myhrvold, C., Kotula, J. W., Hicks, W. M., Conway, N. J. & Silver, P. A. Nat. Commun. 6, 10039 (2015).
Cao, Y. et al. Cell 165, 620–630 (2016).
Maharbiz, M. M. Trends Cell Biol. 22, 617–623 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Ma, H.R., You, L. Polar-opposite fates. Nat Chem Biol 15, 850–852 (2019). https://doi.org/10.1038/s41589-019-0337-z
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41589-019-0337-z
