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New roles for old RNA cap flavors

The N6-methyladenosine modification next to the 5′ RNA cap has dynamic regulatory functions. Recent findings show that this modification regulates the splicing and translational activity of different classes of RNAs.

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Fig. 1: Structure of the 5′ cap on RNAs synthesized by RNA Pol II.


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Correspondence to Richard A. Padgett.

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Padgett, R.A. New roles for old RNA cap flavors. Nat Chem Biol 15, 317–318 (2019).

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