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Transcriptional kinases

Conducting the CTD orchestra

Nature Chemical Biologyvolume 15pages9798 (2019) | Download Citation

The carboxyl-terminal domain (CTD) of RNA polymerase II (Pol II) is post-translationally modified during gene expression. A recent study has identified a CTD kinase, Hrr25, that regulates the termination of noncoding RNA genes by recruiting Rtt103, a key termination factor.

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  1. Department of Functional Genomics and Cancer, IGBMC, Illkirch Graffenstaden, France

    • Carlos Mario Genes Robles
    •  & Frédéric Coin


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The authors declare no competing interests.

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Correspondence to Frédéric Coin.

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