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REDOX REGULATION

Parsing protein sulfinic acid switches

Nature Chemical Biology volume 14, pages 991–993 (2018)Cite this article

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The proteome-wide application of a probe that selectively labels cysteine residues oxidized to the sulfinic acid form reveals the mammalian S-sulfinylome and uncovers novel substrates of the sulfinyl reductase sulfiredoxin, opening yet unexplored realms of cysteine-based redox regulation.

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Fig. 1: Milestone discoveries in redox biology.

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Authors and Affiliations

  1. Université de Lorraine, CNRS, IMoPA, Biopôle, campus Biologie-Santé, Nancy, France

    Sophie Rahuel-Clermont

  2. Institute for Integrative Biology of the Cell (I2BC), CEA–Saclay, CNRS, Université Paris–Saclay, DBJC/SBIGEM, Oxidative Stress & Cancer, Gif-sur-Yvette, France

    Michel B. Toledano

Authors
  1. Sophie Rahuel-Clermont
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  2. Michel B. Toledano
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Correspondence to Michel B. Toledano.

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The authors declare no competing interests.

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Rahuel-Clermont, S., Toledano, M.B. Parsing protein sulfinic acid switches. Nat Chem Biol 14, 991–993 (2018). https://doi.org/10.1038/s41589-018-0151-z

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