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Folding against the wind

Many thermodynamically unfavorable processes in biology are powered by ATP, the energy currency of the cell. New evidence suggests that chaperone-mediated protein stabilization may need to be added to that list.

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Fig. 1: Proteins tend to unfold when facing adverse conditions.

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Correspondence to James C. A. Bardwell.

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Stull, F., Bardwell, J.C.A. Folding against the wind. Nat Chem Biol 14, 329–330 (2018).

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