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Trp-ing upon new repressors

Bioengineers have used directed evolution to generate a new family of synthetic transcription factors based on the tryptophan repressor. The evolved repressor family enables researchers to build new gene circuits for biomedical applications.

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Correspondence to Andreas K. Brödel.

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Brödel, A.K., Isalan, M. Trp-ing upon new repressors. Nat Chem Biol 14, 328–329 (2018).

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