A new single-cell multiomic technique, GAGE-seq, pushes the frontier of single-cell 4D genome analysis by enabling analysis of rare cell populations in complex tissues.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Long, H. K., Prescott, S. L. & Wysocka, J. Cell 167, 1170–1187 (2016).
The ENCODE Project Consortium et al. Nature 583, 699–710 (2020).
Pennacchio, L. A. et al. Nat. Rev. Genet. 14, 288–295 (2013).
Davies, J. O. et al. Nat. Methods 14, 125–134 (2017).
Zhou, T. et al. Nat. Genet. https://doi.org/10.1038/s41588-024-01745-3 (2024).
Chen, H. et al. Genome Biol. 20, 241 (2019).
Liu, Z. et al. Science 380, 1070–1076 (2023).
Baysoy, A. et al. Nat. Rev. Mol. Cell Biol. 24, 695–713 (2023).
Granja, J. M. et al. Nat. Genet. 53, 403–411 (2021).
Hua, P. et al. Nature 595, 125–129 (2021).
Acknowledgements
J.R.H. is supported by the MRC Molecular Haematology Unit (MC_UU_00029/3) and the Wellcome Trust (225220/Z/22/Z). J.O.J.D. is supported by the MRC Molecular Haematology Unit (MC_UU_00029/04), the Wellcome Trust (225220/Z/22/Z), National Institute of Health Research Biomedical Research Centre and Blood and Transplant Research Unit in Precision Cellular Therapeutics (NIHR203311, NIHR203339) and a Lister Prize Fellowship.
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Hughes, J.R., Davies, J.O.J. Single-cell technologies meet Hi-C. Nat Genet 56, 1542–1543 (2024). https://doi.org/10.1038/s41588-024-01855-y
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41588-024-01855-y
