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Single-cell omics to unravel chronic kidney disease

Nature Genetics volume 56, pages 1548–1549 (2024)Cite this article

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We present a multi-omic map of the human kidney in health and disease, using single-cell RNA, single-nuclei RNA, single-nuclei assay for transposase-accessible chromatin sequencing, spot-based and single-cell spatial transcriptomics. This comprehensive approach enables an in-depth understanding of the microenvironments in the diseased kidney.

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Fig. 1: Spatial transcriptomics illuminate the microenvironment of kidneys in disease.

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This is a summary of: Abedini, A. et al. Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression. Nat. Genet. https://doi.org/10.1038/s41588-024-01802-x (2024).

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Single-cell omics to unravel chronic kidney disease. Nat Genet 56, 1548–1549 (2024). https://doi.org/10.1038/s41588-024-01804-9

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