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Ultrasound perception mechanisms revealed by comparisons of microbats and megabats

Microbats utilize ultrasonic echolocation to navigate and locate prey, whereas megabats primarily perceive human-audible sound in daily life. High-quality genomes and single-cell atlases of auditory cortices from microbat and megabat species identify parvalbumin-positive inhibitory neurons and the complexin-1 gene to be crucial in mammalian ultrasound perception.

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Fig. 1: Parvalbumin (PV)-positive inhibitory neurons and Cplx1 are crucial for ultrasound perception in mouse auditory cortices.

References

  1. Li, J. et al. PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice. Proc. Natl Acad. Sci. USA 118, e2101207118 (2021). This paper reports mechanisms regulating ultrasonic hearing in cochlear hair cells.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Carruthers, I. M. et al. Encoding of ultrasonic vocalizations in the auditory cortex. J. Neurophysiol. 109, 1912–1927 (2013). This paper reports the neuronal computations underlying ultrasonic vocalization encoding in the rat auditory cortex at the neurophysiological level.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Teeling, E. C. et al. Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species. Annu. Rev. Anim. Biosci. 6, 23–46 (2018). A review article that emphasizes the importance of high-quality bat genomes for our understanding of the genetic and evolutionary basis of adaptations in bats.

    Article  PubMed  Google Scholar 

  4. Mohrmann, R. et al. Complexins: small but capable. Cell Mol. Life Sci. 72, 4221–4235 (2015). A review article that describes the function of complexins.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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This is a summary of: Liu, M. et al. Ultrasound perception mechanisms revealed by comparisons of microbats and megabats. Nat. Genet. https://doi.org/10.1038/s41588-024-01781-z (2024).

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Ultrasound perception mechanisms revealed by comparisons of microbats and megabats. Nat Genet 56, 1335–1336 (2024). https://doi.org/10.1038/s41588-024-01803-w

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