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Population genetics

Using enormous genealogies to map causal variants in space and time

Nature Genetics volume 55, pages 730–731 (2023)Cite this article

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A new method infers huge gene trees and tests the tree branches for phenotypic associations. This improves power to map the effects of rare variants that are missing from genotype arrays and imputation panels.

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Authors and Affiliations

  1. Department of Genome Sciences, University of Washington, Seattle, WA, USA

    Kelley Harris

  2. Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA

    Kelley Harris

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  1. Kelley Harris
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Correspondence to Kelley Harris.

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The author declares no competing interests.

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Harris, K. Using enormous genealogies to map causal variants in space and time. Nat Genet 55, 730–731 (2023). https://doi.org/10.1038/s41588-023-01389-9

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