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SOMATIC MUTATIONS

Clonal competition in a confined space

Many normal tissues are populated by clonal expansions that compete for space. Colom et al. now show that mutant clones keep other mutant clones in check by effectively annulling one another’s advantages.

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Fig. 1: Clonal dynamics in normal tissue.

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Correspondence to Kamila Naxerova.

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Naxerova, K. Clonal competition in a confined space. Nat Genet 52, 553–554 (2020). https://doi.org/10.1038/s41588-020-0638-x

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