Extended Data Fig. 10: Investigation of NRXN1α isoform changes across development. | Nature Genetics

Extended Data Fig. 10: Investigation of NRXN1α isoform changes across development.

From: Neuronal impact of patient-specific aberrant NRXN1α splicing

Extended Data Fig. 10

a,b, Bar plot of the total read count for each NRXN1α exon along with the fraction that each NRXN1α junction is included in adult dlPFC samples (a) and fetal PFC samples (b); pink boxes represent potential developmentally regulated exons. c, Schematic of NRXN1α isoform structure, with each row representing a unique NRXN1α isoform and each column representing a NRXN1 exon. Colored exons (blue, fetal PFC specific; green, adult dlPFC specific; orange, shared) are spliced into the transcript while blank exons are spliced out. Abundance of each NRXN1α isoform across fetal PFC and adult dlPFC samples.

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