Extended Data Fig. 3: Profile of reviews for each current gene status. | Nature Genetics

Extended Data Fig. 3: Profile of reviews for each current gene status.

From: PanelApp crowdsources expert knowledge to establish consensus diagnostic gene panels

Extended Data Fig. 3

For genes on version 1+ gene panels in the 100,000 Genomes Project, the current rating (green, amber, red, grey) is plotted on the x-axis. For each, the number of reviews from external reviewers (in January 2019) in which the reviewer rated the gene green, amber or red is plotted on the y-axis, demonstrating an overall consensus for the current rating. Genes are converted to grey by a Genomics England curator if reviews suggest that the gene should be removed from the panel, and the majority will be given a red rating by external reviewers.

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