a, Similar to Fig. 6a, however we included an additional null set of SNPs (green). The new null set represent the entire set of heterozygous variants where we computed a p-value. b, Similar to Fig. 6b, however we used eQTLs from naïve T cells that were previously published (Chen, L. et al., Cell. 167, 1398-1414 e24, 2016). Sample sizes can be found in Supplementary Table 1. We computed p-values with a two-sided Mann–Whitney U test.