Supplementary Fig. 7: Abnormal imprints in Setd2mNull FGOs. | Nature Genetics

Supplementary Fig. 7: Abnormal imprints in Setd2mNull FGOs.

From: SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development

Supplementary Fig. 7

a, Snapshots from UCSC browser showing H3K4me3, H3K27me3, H3K36me3, and DNA methylation levels at maternal imprinted loci in control and Setd2mNull FGO, as well as WT and Dnmt3a/b-/- oocytes. Imprinting control regions are shaded. b, Box plot showing the DNA methylation level in regions with H3K4me3, H3K27me3, or neither in Setd2mNull FGO (n = 2). The median of each dataset is shown by center line. The bottom, top edges and whiskers represent the 25th, 75th percentiles and 1.5 times the interquartile range, respectively. P-values (t-test, two sided) are also shown.

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