Supplementary Figure 7: Genotypes of AluJb-P and LIN28BP CRISPR-deleted clones. | Nature Genetics

Supplementary Figure 7: Genotypes of AluJb-P and LIN28BP CRISPR-deleted clones.

From: Transposable elements drive widespread expression of oncogenes in human cancers

Supplementary Figure 7

The CRISPR-mediated genetic breaks are illustrated for H1299 (left) and H838 (right) CRISPR clones. gRNA sequences are illustrated with various colors. AluJb1 KO clones were generated by deleted genomic region between gRNA-A1 and gRNA-A3. AluJb2 KO clones were generated by deleted genomic region between gRNA-A2 and gRNA-A3. LIN28BP KO clones were generated by deleted genomic region between gRNA-L1 and gRNA-L2. Two independent clones were profiled for each set of CRISPR KOs. Two independent clones were profiled for each set of CRISPR KOs. The genotyping gel results were replicated twice in independent experiments.