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Reply to ‘DNA methylation haplotypes as cancer markers’

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Fig. 1: Marker discovery and validation workflow.

References

  1. 1.

    Seoighe, C., Tosh, N. J. & Greally, J. M. Nat. Genet. https://doi.org/10.1038/s41588-018-0185-x (2018).

  2. 2.

    Guo, S. et al. Nat. Genet. 49, 635–642 (2017).

    CAS  Article  Google Scholar 

  3. 3.

    Schultz, M. D. et al. Nature 523, 212–216 (2015).

    CAS  Article  Google Scholar 

  4. 4.

    Lokk, K. et al. Genome Biol. 15, r54 (2014).

    Article  Google Scholar 

  5. 5.

    Sun, K. et al. Proc. Natl. Acad. Sci. USA 112, E5503–E5512 (2015).

    CAS  Article  Google Scholar 

Download references

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D.D. and K.Z. performed all analyses and wrote the manuscript.

Corresponding author

Correspondence to Kun Zhang.

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Competing interests

D.D. and K.Z. were listed as co-inventors on patent applications related to this study. K.Z. is a co-founder and scientific advisor of Singlera Genomics.

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Diep, D., Zhang, K. Reply to ‘DNA methylation haplotypes as cancer markers’. Nat Genet 50, 1063–1066 (2018). https://doi.org/10.1038/s41588-018-0186-9

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