Supplementary Figure 4: Integrated kinetics of gene expression, compartmentalization and chromatin state. | Nature Genetics

Supplementary Figure 4: Integrated kinetics of gene expression, compartmentalization and chromatin state.

From: Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming

Supplementary Figure 4

(a) Dynamics of average gene expression versus PC1 (left) and H3K4Me2 levels versus PC1 (right) for all 20 individual switching clusters (see Fig.2g). Arrows indicate time points were the correlation between either expression or H3K4Me2 and PC1 is lost. Sample sizes are shown in panel b. (b) Summarized gene ontology (GO) annotation of the 20 switching clusters grouped by switching type and with relationship class (gene expression versus PC1; concom. = concomitant) indicated. Error bars in all plots denote SEM.

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