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Monitoring gene expression in the brain with a blood test

We developed synthetic serum markers that can be expressed in the brain but are transported into the blood, enabling minimally invasive monitoring of gene expression in the brain with a simple blood test.

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Fig. 1: Monitoring gene expression with RMAs.


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This is a summary of: Lee, S. et al. Engineered serum markers for non-invasive monitoring of gene expression in the brain. Nat. Biotechnol. (2024).

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Monitoring gene expression in the brain with a blood test. Nat Biotechnol (2024).

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