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Public biotech in 2022 — the numbers

Nature Biotechnology volume 41, page 1185 (2023)Cite this article

Mergers were still in the doldrums, although there were several noteworthy multi-billion-dollar acquisitions; Amgen’s $27.8 billion acquisition of Horizon Therapeutics (still under review by the Federal Trade Commission) sits at the top. And the beat goes on into this year with several mega-acquisitions in the first half of the year, including the $43 billion acquisition of antibody–drug conjugate pioneer Seagen by Pfizer. More deals are anticipated as pharma adjusts to the post-Inflation Reduction Act environment, as well as to some noteworthy patent expirations.

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Fig. 1: Biotech IPO activity since 2011, showing the amount raised ($ millions) and the number of companies going public.
Fig. 2: NASDAQ biotech index over time.
Fig. 3: Number of biotech companies and employees by market capitalization.
Fig. 4: Public biotech company revenue, R&D spending and net profit or loss by market capitalization.

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  1. Senior Editor, Nature Biotechnology https://www.nature.com/nbt/

    Laura DeFrancesco

  2. Turku, Finland

    Riku Lähteenmäki

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  1. Laura DeFrancesco
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  2. Riku Lähteenmäki
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DeFrancesco, L., Lähteenmäki, R. Public biotech in 2022 — the numbers. Nat Biotechnol 41, 1185 (2023). https://doi.org/10.1038/s41587-023-01923-4

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