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‘Clicked’ drugs: researchers prove the remarkable chemistry in humans

Nature Biotechnology volume 41, pages 883–885 (2023)Cite this article

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Bioorthogonal click chemistry is being used in patients to help target cancer medicines and diagnostic imaging agents

Click chemistry has become an indispensable tool in biological research and drug discovery, and its pioneers won last year’s Nobel Prize in Chemistry for their work. “Those chemistries are all over the place in the biopharma industry,” says Carolyn Bertozzi of Stanford University, one of the prize winners, who is also a scientific advisor to Shasqi. “What Shasqi has done here is broken through the glass ceiling of actually doing the chemistry in the human patient.”

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  • 20 July 2023

    In the version of this article initially published, Carolyn Bertozzi was described as being at Stanford during development of the copper-free click reaction; she was at University of California, Berkeley, as is now reflected in the HTML and PDF versions of the article.

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  1. Penrith, UK

    Mark Peplow

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Peplow, M. ‘Clicked’ drugs: researchers prove the remarkable chemistry in humans. Nat Biotechnol 41, 883–885 (2023). https://doi.org/10.1038/s41587-023-01860-2

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