Existing methods to infer cell–cell communication from single-cell RNA-sequencing data fail to leverage the full information structure of the data, generally by operating at the level of the cell type or cluster. We describe a framework called Scriabin to perform this analysis at the level of the individual cell.
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References
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This is a summary of: Wilk, A. J., Shalek, A. K., Holmes, S. & Blish, C. A. Comparative analysis of cell–cell communication at single-cell resolution. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01782-z (2023).
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Inferring cell–cell communication at single-cell resolution. Nat Biotechnol 42, 390–391 (2024). https://doi.org/10.1038/s41587-023-01834-4
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DOI: https://doi.org/10.1038/s41587-023-01834-4
