Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Patents
  • Published:

Patents

Who counts as an inventor? Seniority and gender in 430,000 biomedical inventor–researcher teams

An analysis of the overlap of authors and inventors in a comprehensive citation map of patents to the biomedical research literature reveals significant and persistent disparities within the commercialization process.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Publications that are cited by their authors as part of patents are distinct from the broader biomedical research literature.
Fig. 2: Research team members’ seniority-based representation in patent inventorship status (N = 430,198).
Fig. 3: Research team demographic representation as a function of authorship position.

Data availability

Patent data is publicly available at https://console.cloud.google.com/marketplace/product/google_patents_public_datasets/google-patents-public-data, and the PubMed publication information can be downloaded at ftp://ftp.ncbi.nlm.nih.gov/pubmed/baseline. The code and data are available at https://github.com/amanjuna/patent_impact.

Code availability

The code and data are available at https://github.com/amanjuna/patent_impact.

References

  1. Lutchen, K., Ayers, J., Gallagher, S. & Abu-Taleb, L. Sci. Transl. Med. 3, 110cm32 (2011).

    Article  PubMed  Google Scholar 

  2. Huang, S. et al. Nat. Biotechnol. 39, 293–301 (2021).

    Article  CAS  PubMed  Google Scholar 

  3. Forman, S. M., Lo, A. W., Shilling, M. & Sweeney, G. K. Preprint at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2649260 (2015).

  4. Chitale, S., Lawler, C. & Macfarlane, S. Nat. Biotechnol. 38, 263–270 (2020).

    Article  CAS  PubMed  Google Scholar 

  5. Manual of Patent Examining Procedure. 707.05 Citation of References [R-6] (updated June 2020).

  6. Paul, S. M. et al. Nat. Rev. Drug Discov. 9, 203–214 (2010).

    Article  CAS  PubMed  Google Scholar 

  7. Coller, B. S. & Califf, R. M. Sci. Transl. Med. 1, 10cm9 (2009).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Meyer, M. Res. Policy 29, 409–434 (2000).

    Article  Google Scholar 

  9. Trajtenberg, M. & Jaffe, A. B. Patents, Citations, and Innovations: A Window on the Knowledge Economy (MIT Press, 2002).

  10. Ahmadpoor, M. & Jones, B. F. Proc. Natl Acad. Sci. USA 116, 13885–13890 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Jones, B. F. & Weinberg, B. A. Proc. Natl Acad. Sci. USA 108, 18910–18914 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Jefferson, O. A. et al. Nat. Biotechnol. 36, 31–39 (2018).

    Article  CAS  PubMed  Google Scholar 

  13. Fagnan, D. E., Yang, N. N., McKew, J. C. & Lo, A. W. Sci. Transl. Med. 7, 276ps3 (2015).

    Article  PubMed  Google Scholar 

  14. Wu, L., Wang, D. & Evans, J. A. Nature 566, 378–382 (2019).

    Article  CAS  PubMed  Google Scholar 

  15. Ross, M. B. et al. Nature 608, 135–145 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Manjunath, A. et al. Nat. Biotechnol. 39, 678–683 (2021).

    Article  CAS  PubMed  Google Scholar 

  17. Wislar, J. S., Flanagin, A., Fontanarosa, P. B. & Deangelis, C. D. BMJ 343, d6128 (2011).

    Article  PubMed  PubMed Central  Google Scholar 

  18. Broderick, N. A. & Casadevall, A. eLife 8, e36399 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  19. Huang, J., Gates, A. J., Sinatra, R. & Barabási, A. L. Proc. Natl Acad. Sci. USA 117, 4609–4616 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Ding, W. W., Murray, F. & Stuart, T. E. Science 313, 665–667 (2006).

    Article  CAS  PubMed  Google Scholar 

  21. Koning, R., Samila, S. & Ferguson, J. P. Science 372, 1345–1348 (2021).

    Article  CAS  PubMed  Google Scholar 

  22. Kaminski, D. & Geisler, C. Science 335, 864–866 (2012).

    Article  CAS  PubMed  Google Scholar 

  23. Lissoni, F., Montobbio, F. & Zirulia, L. Ind. Corp. Change 29, 1471–1482 (2020).

    Article  Google Scholar 

  24. Lissoni, F., Montobbio, F. & Zirulia, L. J. Econ. Behav. Organ. 95, 49–69 (2013).

    Article  Google Scholar 

  25. Noyons, E. C. M., van Raan, A. F. J., Grupp, H. & Schmoch, U. Res. Policy 23, 443–457 (1994).

    Article  Google Scholar 

  26. Noyons, E. C. M. et al. Mapping Excellence in Science and Technology across Europe: Nanoscience and Nanotechnology. Report of Project EC-PPLS CT-2002-0001 to the European Commission (October 2003).

Download references

Acknowledgements

The authors thank M. Lemley, R. Malenka, K. Nikolich and R. Weisberg for feedback and advice. J.Z. is supported by grants from the Silicon Valley Foundation and the Chan Zuckerberg Initiative.

Author information

Authors and Affiliations

Authors

Contributions

A.M., J.Y.Z. and I.K. developed concepts and experiments. A.M., N.K., J.M., A.G., E.U., R.U. and A.S. performed data extraction, mapping and processing. A.M. and A.S. prepared visualizations. I.K. and A.M. wrote the paper, with help from J.Y.Z. and A.S. J.Y.Z. and I.K. supervised the work.

Corresponding authors

Correspondence to Anoop Manjunath, James Y. Zou or Ishan Kumar.

Ethics declarations

Competing interests

The authors declare no competing interests.

Peer review

Peer review information

Nature Biotechnology thanks Osmat Jefferson and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

Supplementary information

Supplementary Information

Supplementary Figs. 1–7, Tables 1 and 2, and Methods

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Manjunath, A., Kahrobai, N., Manjunath, J. et al. Who counts as an inventor? Seniority and gender in 430,000 biomedical inventor–researcher teams. Nat Biotechnol 41, 610–614 (2023). https://doi.org/10.1038/s41587-023-01771-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41587-023-01771-2

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing