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Imaging large cell populations with fast, automated super-resolution

Leveraging advances in hardware and probes, we have combined innovations in optics and algorithms to allow automated single-molecule-based super-resolution imaging at unprecedented throughput. This approach allows us to obtain nanoscale information from large cell populations, bridging the gap between imaging and indirect ensemble methods.

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Fig. 1: 3D super-resolution imaging of 10,000 cells in a day.


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This is a summary of: Barentine, A. E. S. et al. An integrated platform for high-throughput nanoscopy. Nat. Biotechnol. (2023).

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Imaging large cell populations with fast, automated super-resolution. Nat Biotechnol (2023).

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