Leveraging advances in hardware and probes, we have combined innovations in optics and algorithms to allow automated single-molecule-based super-resolution imaging at unprecedented throughput. This approach allows us to obtain nanoscale information from large cell populations, bridging the gap between imaging and indirect ensemble methods.
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This is a summary of: Barentine, A. E. S. et al. An integrated platform for high-throughput nanoscopy. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01702-1 (2023).
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Imaging large cell populations with fast, automated super-resolution. Nat Biotechnol (2023). https://doi.org/10.1038/s41587-023-01711-0