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Optical microscopy gets down to angstroms

Super-resolution microscopy at ångström precision could pave the way to optical structural biology in cells.

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Fig. 1: MINSTED microscopy in context.

References

  1. Weber, M. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-022-01519-4 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Weber, M. et al. Nat. Photonics 15, 361–366 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Hell, S. & Wichmann, J. Opt. Lett. 19, 780–782 (1994).

    Article  CAS  PubMed  Google Scholar 

  4. Vicidomini, G. et al. Nat. Methods 8, 571–575 (2011).

    Article  CAS  PubMed  Google Scholar 

  5. Göttfert, F. et al. Proc. Natl Acad. Sci. USA 114, 2125–2130 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Balzarotti, F. et al. Science 355, 606–612 (2017).

    Article  CAS  PubMed  Google Scholar 

  7. Jungmann, R. et al. Nat. Methods 11, 313–318 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Tuijtel, M., Koster, A., Jakobs, S., Faas, F. & Sharp, T. Sci. Rep. 9 (2019).

  9. Harke, B., Ullal, C., Keller, J. & Hell, S. Nano Lett. 8, 1309–1313 (2008).

    Article  CAS  PubMed  Google Scholar 

  10. Huang, B., Wang, W., Bates, M. & Zhuang, X. Science 319, 810–813 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Correspondence to Suliana Manley.

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Tortarolo, G., Manley, S. Optical microscopy gets down to angstroms. Nat Biotechnol 41, 473–474 (2023). https://doi.org/10.1038/s41587-022-01544-3

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