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PROTEIN STRUCTURE PREDICTION

A language model beats alphafold2 on orphans

Nature Biotechnology volume 40, pages 1576–1577 (2022)Cite this article

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Protein structure prediction with a language model improves accuracy for orphan and designed proteins.

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Fig. 1: Distance restraints from experiment or language models in protein structure calculations.

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Authors and Affiliations

  1. Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA

    Jennifer M. Michaud & James S. Fraser

  2. Profluent Bio, Oakland, CA, USA

    Ali Madani

Authors
  1. Jennifer M. Michaud
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  2. Ali Madani
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  3. James S. Fraser
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Correspondence to James S. Fraser.

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Michaud, J.M., Madani, A. & Fraser, J.S. A language model beats alphafold2 on orphans. Nat Biotechnol 40, 1576–1577 (2022). https://doi.org/10.1038/s41587-022-01466-0

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