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Brand-name market exclusivity for nebulizer therapy to treat asthma and COPD

Nature Biotechnology volume 40, pages 1319–1325 (2022)Cite this article

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Manufacturers of brand-name nebulizer solutions have employed a variety of strategies to preserve market dominance over their products but have been less successful than manufacturers of brand-name inhalers in preventing generic competition.

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Fig. 1: Brand-name market exclusivity and generic competition for nebulizer solutions.
Fig. 2: Brand-name market exclusivity and generic competition for inhalers.
Fig. 3: Brand-name market exclusivity and generic competition for nebulizer solutions with corresponding inhalers.

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Acknowledgements

This work was funded by the Commonwealth Fund, as well as from a grant (National Institutes of Health 5T32HL007633-36) to W.B.F. A.S.K.’s work was also supported by Arnold Ventures. R.B.’s work is funded by an O’Brien Institute of Public Health catalyst grant for equitable pharmaceutical innovation and access to medicines. The funders had no role in the design and conduct of the study; collection, management, analysis or interpretation of the data; review or approval of the manuscript; or decision to submit the manuscript for publication.

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Authors and Affiliations

  1. Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    William B. Feldman, Doni Bloomfield, Reed F. Beall & Aaron S. Kesselheim

  2. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    William B. Feldman

  3. Harvard Medical School, Boston, MA, USA

    William B. Feldman, Doni Bloomfield & Aaron S. Kesselheim

  4. Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

    Reed F. Beall

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  1. William B. Feldman
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  2. Doni Bloomfield
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Corresponding author

Correspondence to William B. Feldman.

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Competing interests

Outside the scope of the work, W.B.F. serves as a consultant for Alosa Health and as an expert witness in litigation against inhaler manufacturers. W.B.F. also served as a consultant to Aetion and received an honorarium for a presentation to Blue Cross Blue Shield of Massachusetts. D.B. currently serves as a judicial clerk at the US Court of Appeals for the District of Columbia Circuit. This Comment was drafted before his clerkship and represents only his personal views.

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Feldman, W.B., Bloomfield, D., Beall, R.F. et al. Brand-name market exclusivity for nebulizer therapy to treat asthma and COPD. Nat Biotechnol 40, 1319–1325 (2022). https://doi.org/10.1038/s41587-022-01451-7

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