Correction to: Nature Biotechnology https://doi.org/10.1038/s41587-021-01049-5, published online 9 September 2021.

In the version of this Article initially published, Extended Data Fig. 4 had incorrect coloration and an incorrect legend. PacBio long reads matched against CLINVAR variants were incorrectly colored in light green instead of brown (top right of panel a). In the bottom shared legend (below panel c), Nanopore was incorrectly identified with a brown circle instead of dark green. This figure has been corrected with a new legend for CLINVAR/OMIM variant analysis (below panel b) and a separate, corrected legend for exam variant analysis at the bottom of the figure.

The online version of the article has been updated.