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Responsible governance of gene editing in agriculture and the environment

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Fig. 1: Six principles for governance of gene-edited products in agriculture and the environment.


  1. Karkute, S. G., Singh, A. K., Gupta, O. P., Singh, P. M. & Singh, B. Front. Plant Sci. 8, 1635 (2017).

    Article  Google Scholar 

  2. National Academies of Sciences, Engineering, and Medicine. Preparing for Future Products of Biotechnology (National Academies Press, 2017);

  3. Hua, K. et al. Mol. Plant 12, 1047–1059 (2019).

    Article  CAS  Google Scholar 

  4. Redford, K.H., Brooks, T.M., Macfarlane, N.B.W. & Adams, J.S., eds. Genetic Frontiers for Conservation: An Assessment of Synthetic Biology and Biodiversity Conservation (IUCN, 2019);

  5. Clapp, J. & Ruder, S. L. Glob. Environ. Polit. 20, 49–69 (2020).

    Article  Google Scholar 

  6. Rose, K. M., Brossard, D. & Scheufele, D. A. Environ. Commun. 14, 1017–1031 (2020).

    Article  Google Scholar 

  7. Jordan, N. R. et al. EMBO Rep. 18, 1683–1687 (2017).

    Article  CAS  Google Scholar 

  8. Kofler, N. et al. Science 362, 527–529 (2018).

    Article  CAS  Google Scholar 

  9. Kuzma, J. & Grieger, K. Science 370, 916–918 (2020).

    Article  CAS  Google Scholar 

  10. National Academies of Sciences, Engineering, and Medicine. Genetically Engineered Crops: Experiences and Prospects (National Academies Press, 2016);

  11. Abdallah, N. A., Prakash, C. S. & McHughen, A. G. GM Crops Food 6, 183–205 (2015).

    Article  Google Scholar 

  12. Agapito-Tenfen, S. Z., Okoli, A. S., Bernstein, M. J., Wikmark, O. G. & Myhr, A. I. Front Plant Sci. 9, 1874 (2018).

    Google Scholar 

  13. Hudson, M. et al. Nat. Rev. Genet. 21, 377–384 (2020).

    Article  CAS  Google Scholar 

  14. Norris, A. L. et al. Nat. Biotechnol. 38, 163–164 (2020).

    Article  CAS  Google Scholar 

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We appreciate comments on the draft principles provided by B. Dass, J. Delborne, S. Eskin, S. James, N. Jordan, T. Kuiken, K. Redford, S. Scherr, and K. H. Tountas. We thank the Grantham Foundation for support to J. Shapiro of Keystone Policy Center for facilitating our dialog and thank our respective organizations for support of this work.

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Conceptualization: G.J., M.D., D.R.G., A.G., T.G. and M.H. Writing—original draft: D.R.G. Writing—review and editing: G.J., M.D., A.G., T.G., M.H. and D.R.G.

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Correspondence to Doria R. Gordon.

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Gordon, D.R., Jaffe, G., Doane, M. et al. Responsible governance of gene editing in agriculture and the environment. Nat Biotechnol 39, 1055–1057 (2021).

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