Researchers hope that antisense oligo clinical trial failures in Huntington’s will shed light on mechanism and drug biodistribution and galvanize ongoing drug development efforts.
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Change history
21 June 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00987-4
26 July 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-01017-z
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Sheridan, C. Questions swirl around failures of disease-modifying Huntington’s drugs. Nat Biotechnol 39, 650–652 (2021). https://doi.org/10.1038/s41587-021-00955-y
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DOI: https://doi.org/10.1038/s41587-021-00955-y