Extended Data Fig. 5: Comparison of autoencoding and segmentation-based decompression. | Nature Biotechnology

Extended Data Fig. 5: Comparison of autoencoding and segmentation-based decompression.

From: Compressed sensing for highly efficient imaging transcriptomics

Extended Data Fig. 5

Individual gene images recovered (magenta) using the autoencoding algorithm (left) or the segmentation based algorithm (right) are overlaid with direct measurement (green) of the genes in the same tissue sections (white: direct overlap). For segmentation-based decompression, the decompressed signal for each gene is projected uniformly over each segmentation mask. Scale bar: 500um. Representative fields of view were selected to highlight expression of indicated genes, while quantification of overlap (correlation) was calculated using all cells in a given tissue section, or using randomly selected testing cells (where indicated).

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