Recent patents related to systems and methods of imaging.
|US 10,614,993||Methods and apparatus for an imaging system comprising a multitude of chemical-emitting elements upon a substrate. In some embodiments the substrate may be approximately round with a radius of approximately one inch. Various methods relating to using and producing an imaging system of chemical emitters are disclosed.||Flitsch FA||Flitsch FA||4/7/2020|
|US 10,473,644||A system for assaying forces applied by cells, including an optically transparent substrate comprising a soft material having a Young’s modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, and the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescence emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.||The Regents of the University of California (Oakland, CA, USA)||Di Carlo D, Tseng P, Pushkarsky I||11/12/2019|
|US 10,430,955||Systems and methods for high-content screening for microscope imaging. In some embodiments, the system comprises a microscope and a processor configured to implement a slide loader module, a reference imager module, a slide imager module, a region of interest (ROI) finder module, a compare imager module, a calibrator module and an image stitcher module.||The Regents of the University of California (Oakland, CA, USA)||Frise E, Booth B, McParland C, Beattie K, Fisher B, Hammonds AS, Celniker SE||10/1/2019|
|US 10,376,600||A method for early-stage pathology detection, location, imaging, evaluation and treatment of cells and/or extracellular vesicles in the circulation.||Peyman GA||Peyman GA||8/13/2019|
|US 10,294,510||Methods and compositions for high-throughput and highly multiplexed imaging with programmable nucleic acid probes.||President and Fellows of Harvard College (Cambridge, MA)||Yin P, Agasti S, Chen X, Jungmann R||5/21/2019|
|US 10,077,463||Photochemical crosslinkers and photocleavable crosslinkers and their uses in methods for cell selection from cell cultures. The photochemical crosslinkers comprise a fluorescent dye and a radical generator. The photocleavable crosslinkers comprise a photocleavable linker linking two electrophilic groups. Also, systems for imaging cells comprising a plurality of cells crosslinked to extracellular matrix proteins using a crosslinker as described, an imaging apparatus, an illuminating apparatus, and software for image processing.||President and Fellows of Harvard College (Cambridge, MA)||Cohen AE, Chien M-P||9/18/2018|