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Genome editing in animals: why FDA regulation matters

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Fig. 1: Template plasmid integration at the target site of genome-edited animals.


  1. Norris, A. et al. Nat. Biotechnol. (2020).

  2. Carlson, D. F. et al. Nat. Biotechnol. 34, 479–481 (2016).

    Article  CAS  Google Scholar 

  3. Nagahata, H. J. Vet. Med. Sci. 66, 1475–1482 (2004).

    Article  Google Scholar 

  4. Shuster, D. E., Kehrli, M. E. Jr., Ackermann, M. R. & Gilbert, R. O. Proc. Natl Acad. Sci. USA 89, 9225–9229 (1992).

    Article  CAS  Google Scholar 

  5. Kumar, V. & Sharma, A. Agric. Rev. (Karnal) 30, 293–300 (2009).

    Google Scholar 

  6. Olson, E. N., Arnold, H.-H., Rigby, P. W. & Wold, B. J. Cell 85, 1–4 (1996).

    Article  CAS  Google Scholar 

  7. Meier, I. D. et al. FASEB J. 24, 1714–1724 (2010).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Steven M. Solomon.

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Solomon, S.M. Genome editing in animals: why FDA regulation matters. Nat Biotechnol 38, 142–143 (2020).

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