Supplementary Figure 3: Motif analysis of phosphopeptides in selected PDTs. | Nature Biotechnology

Supplementary Figure 3: Motif analysis of phosphopeptides in selected PDTs.

From: Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

Supplementary Figure 3

Phosphopeptides were matched to predefined phosphorylation motifs that are common in kinase substrates (a) or to predicted kinase-substrate (Netphorest) groups (b). Enrichment was calculated as Log2[(k/m)/(q/t)] for (a) or as (k/m)/(q/t) for (b), where k is number of phosphosites in PDT that match the named motif/Netphorest group, m is total number of phosphosites in PDTs, q is total number of phosphosites in motif/Netphorest group, and t is total number of phosphosites. Full sets of motif/Netphorest groups in different PDTs are shown in Supplementary Dataset 4.

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