Supplementary Figure 7: Metabolite-microbiome genera correlations in the validation cohort. | Nature Biotechnology

Supplementary Figure 7: Metabolite-microbiome genera correlations in the validation cohort.

From: Blood metabolome predicts gut microbiome α-diversity in humans

Supplementary Figure 7

A) Spearman correlation of each of the 11 strongest metabolites identified in the discovery set (rows) with microbiome genera (columns) in the validation cohort, correcting for multiple hypothesis testing (Benjamini-Hochberg FDR<0.05). Only genus-metabolite correlations that were significant in the discovery cohort were considered. The top bar graph represents the fractional abundance of each genus in the validation cohort, with bars colored by phylum. B) The number of significant Spearman correlations of each of the 11 metabolites retained by all 10 LASSO models (rows) with microbiome genera in the discovery and validation cohorts, correcting for multiple hypothesis testing (Benjamini-Hochberg FDR<0.05).

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