Supplementary Figure 2: Distribution of repair outcomes. | Nature Biotechnology

Supplementary Figure 2: Distribution of repair outcomes.

From: Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells

Supplementary Figure 2

(a) Distribution of the edit efficiency (left) and indel diversity (right) of the repair outcomes in T cells. We use the entropy of the distribution of the reads over the indel types as a metric to quantify the diversity of the repair outcomes. If there is exactly one repair outcome in all of the reads, then the entropy is 0. Higher entropy means that the repair outcomes are more diverse. (b) Distribution of the fraction of total reads with an insertion (left) and deletion (right) in T cells. (c) Distribution of the average insertion length given an insertion (left) and average deletion length given a deletion (right) in the repair outcomes of T cells.

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