A survey of the CRISPR patent landscape shows the improvement of technology, a diversity of potential sectors of application, and a new geopolitical balance of forces in the field.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
The global patent landscape of emerging infectious disease monkeypox
BMC Infectious Diseases Open Access 15 April 2024
-
Engineering apomixis in crops
Theoretical and Applied Genetics Open Access 18 May 2023
-
Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies
Biological Research Open Access 20 October 2022
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Jinek, M. et al. Science 337, 816–821 (2012).
Cong, L. et al. Science 339, 819–823 (2013).
Mali, P. et al. Science 339, 823–826 (2013).
Harrison, C. Nat. Biotechnol. 36, 209 (2018).
Lim, D. Pharm. Pat. Anal. 7, 141–145 (2018).
Sherkow, S. CRISPR J. 1, 309–311 (2018).
Parthasarathy, S. Nature 562, 486–488 (2018).
Egelie, K. J., Graff, G. D., Strand, S. P. & Johansen, B. Nat. Biotechnol. 34, 1025–1031 (2016).
Smith, J. A., Arshad, Z., Thomas, H., Carr, A. J. & Brindley, D. A. Nat. Biotechnol. 35, 210–214 (2017).
Maus, M. V. & Levine, B. L. Oncologist 21, 608–617 (2016).
Feng, W. et al. Int. J. Mol. Sci. 16, 6545–6556 (2015).
Ferreira, R., David, F. & Nielsen, J. J. Ind. Microbiol. Biotechnol. 45, 467–480 (2018).
Ricroch, A. E., Ammann, K. & Kuntz, M. EMBO Rep. 17, 1365–1369 (2016).
Bhat, S. A. et al. Vet. World 10, 1361–1366 (2017).
Sherkow, J. S. Yale J. Biol. Med. 90, 667–672 (2017a).
Sherkow, J. S. J. Law Biosci. 4, 565–576 (2017b).
Sherkow, J. S. EMBO Rep. 18, 1047–1051 (2017c).
Callaway, E. Nature 560, 16 (2018).
Rodriguez-Navarro, A. & Narin, F. Sci. Public Policy 45, 14–23 (2018).
Kuntz, M. & Berezow, A. Timidity and a hostility to competition have left Europe a scientific wasteland. The Telegraph (5 September 2017).
Belda, I., Penas, G., Marquina, D. & Santos, A. Trends Biotechnol. 32, 393–395 (2014).
Brinegar, K. et al. Crit. Rev. Biotechnol. 37, 1–12 (2017).
De Rassenfosse, G. & Raiteri, E. Technology protectionism and the patent system: strategic technologies in China. SSRN. https://doi.org/10.2139/ssrn.2803379 (2016).
Acknowledgements
The contributions of U. Del Ghingaro and M. Jamet to early stages of this work are gratefully acknowledged. The authors also thank M. Brites Teixeira for comments and Patent Pulse for allowing us temporary free access to their database.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Supplementary information
Supplementary Note
Criteria used for patent selection and for further categorization
Supplementary Table 1
CRISPR patent compilation
Rights and permissions
About this article
Cite this article
Martin-Laffon, J., Kuntz, M. & Ricroch, A.E. Worldwide CRISPR patent landscape shows strong geographical biases. Nat Biotechnol 37, 613–620 (2019). https://doi.org/10.1038/s41587-019-0138-7
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41587-019-0138-7
This article is cited by
-
The global patent landscape of emerging infectious disease monkeypox
BMC Infectious Diseases (2024)
-
Making genome editing a success story in Africa
Nature Biotechnology (2024)
-
Engineering apomixis in crops
Theoretical and Applied Genetics (2023)
-
Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies
Biological Research (2022)