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01 November 2019
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
References
Pharmaceutical Research and Manufacturers of America (PhRMA). Prescription medicines: costs in context. Advocacy: Cost & Value of Medicines https://www.phrma.org/report/prescription-medicines-costs-in-context (2016).
Greenwood, J. U.S. drug costs must be weighed against benefits. Bloomberg News http://www.bloomberg.com/news/articles/2015-12-28/u-s-drug-costs-must-be-weighed-against-benefits (2015).
Scannell, J. W., Blanckley, A., Boldon, H. & Warrington, B. Nat. Rev. Drug Discov. 11, 191–200 (2012).
Brennan, Z. Congressmen investigate ‘shadow pricing’ of MS drugs. Regulatory Focus https://www.raps.org/regulatory-focus%E2%84%A2/news-articles/2017/8/congressmen-investigate-shadow-pricing-of-ms-drugs (2017).
Kelley, T. U.S. insulin prices rise as Sanofi, Novo await rivals. Bloomberg News https://www.bloomberg.com/news/articles/2013-08-15/u-s-insulin-prices-rise-as-sanofi-novo-await-rivals (2013).
Langreth, R. Hot drugs show sharp price hikes in shadow market. Bloomberg News https://www.bloomberg.com/news/articles/2015-05-06/diabetes-drugs-compete-with-prices-that-rise-in-lockstep (2015).
Barrett, P. & Langreth, R. The crazy math behind drug prices. Bloomberg Businessweek https://www.bloomberg.com/news/articles/2017-06-29/the-crazy-math-behind-drug-prices (2017).
Persistence Market Research. Biosimilar Market: Pricing Analysis 2006–2017 (Persistence Market Research, New York, 2017).
Hartung, D. M., Bourdette, D. N., Ahmed, S. M. & Whitham, R. H. Neurology 84, 2185–2192 (2015).
Benmeleh, Y. FDA deals blow to Teva’s defense plan with ruling on Bendeka. Bloomberg News http://www.bloomberg.com/news/articles/2016-03-29/fda-deals-blow-to-teva-s-defense-plan-with-ruling-on-bendeka (2016).
Serebrov, M. PBMs: The ‘shadow’ players in the drug pricing skirmish? BioWorld http://www.bioworld.com/content/pbms-shadow-players-drug-pricing-skirmish-0 (2016).
Tufts Center for the Study of Drug Development (CSDD). Cost of Developing a New Drug (Tufts CSDD, Boston, 2014).
Loftus, P. U.S. investigates drugmaker contracts with pharmacy-benefit managers. The Wall Street Journal https://www.wsj.com/articles/u-s-investigates-drugmaker-contracts-with-pharmacy-benefit-managers-1462895700 (2016).
Wingfield, N., Thomas, K. & Abelson, R. Amazon, Berkshire Hathaway and JPMorgan team up to try to disrupt health care. The New York Times https://www.nytimes.com/2018/01/30/technology/amazon-berkshire-hathaway-jpmorgan-health-care.html (2018).
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Rathore, A.S., Shereef, F. Shadow pricing and the art of profiteering from outdated therapies. Nat Biotechnol 37, 217–220 (2019). https://doi.org/10.1038/s41587-019-0049-7
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DOI: https://doi.org/10.1038/s41587-019-0049-7