Correction to: Nature https://doi.org/10.1038/s41586-022-05255-2 Published online 28 September 2022

In the version of this article initially published, the orientation of Figure 3a (“+PUM” at top, “Untreated” at bottom) was incorrect and has been amended to read left-to-right, in alignment with Figure 3e, in the HTML and PDF versions of the article