Extended Data Fig. 5: Features of driver mutations. | Nature

Extended Data Fig. 5: Features of driver mutations.

From: In silico saturation mutagenesis of cancer genes

Extended Data Fig. 5

a, Radial plots representing the contributions of different features (via SHAP values) to the classification of five selected driver mutations. b, Two-dimensional representation (via t-distributed stochastic neighbour embedding; t-SNE) of the combination of features relevant to the classification of all driver mutations across genes and tumour types. Mutations are coloured according to the mode of action (left) of the genes they affect, clusters (centre) resulting from the similarity of their SHAP values (Fig. 2d) and the complexity index (right) of the model used to classify them

Source data.

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