Extended Data Fig. 5: The replication-stress response, probably caused by lrr-1 and nucleotide insufficiency, promotes cell extrusion. | Nature

Extended Data Fig. 5: The replication-stress response, probably caused by lrr-1 and nucleotide insufficiency, promotes cell extrusion.

From: Replication stress promotes cell elimination by extrusion

Extended Data Fig. 5

ad, Confocal fluorescence micrographs showing the localization of RPA-1–YFP in ABplpappap (arrowheads) in ced-3(lf); ltIs44; opIs263 embryos after the indicated RNAi treatment. Insets, magnified views of ABplpappap. e, Genes identified as suppressors of the sterility of lrr-1(lf) mutants19 were tested for suppression of cell extrusion. f, Nomarski micrograph showing a cell extruded (arrow) from a wild-type embryo after gmpr-1(RNAi) treatment. Scale bars, 10 μm.

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