Extended Data Fig. 4: Attraction to a newly learned food odour is enhanced by hunger and optogenetic stimulation. | Nature

Extended Data Fig. 4: Attraction to a newly learned food odour is enhanced by hunger and optogenetic stimulation.

From: Hunger enhances food-odour attraction through a neuropeptide Y spotlight

Extended Data Fig. 4

a, Timeline of two-choice behavioural assay before learning. b, Investigation times of fed (left) and fasted (right) wild-type male mice to pheromones (unfilled bars) and strawberry-gelatin odour (filled bars) before learning. n = 10 mice, data are mean ± s.e.m., lines with triangles represent individual mice. **P < 0.01, two-tailed Wilcoxon test (P fed: 0.002; P fasted: 0.002). c, Timeline of learning paradigm and two-choice behavioural assay after learning. d, Investigation times to pheromones (unfilled bars) and strawberry-gelatin odour (filled bars) after learning in wild-type fed mice, wild-type fasted mice, wild-type fed mice after arcuate nucleus injection of AAV-DIO-ChR2 and PVT illumination (control), and Agrp-ires-cre fed mice after arcuate nucleus injection of AAV-DIO-ChR2 and PVT illumination. n = 6 (wild-type fed, fasted), 4 (control, PVT) and 8 (AGRP-ON, PVT) mice, data are mean ± s.e.m., lines with triangles represent individual mice. *P < 0.05, **P < 0.01, two-tailed Wilcoxon test (P values from left to right: >0.99, 0.03, 0.88, 0.008).

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