Fig. 3: Vaccine platforms used for SARS-CoV-2 vaccine development. | Nature

Fig. 3: Vaccine platforms used for SARS-CoV-2 vaccine development.

From: SARS-CoV-2 vaccines in development

Fig. 3

a, A schematic of the structural proteins of the SARS-CoV-2 virion, including the lipid membrane, the genomic RNA covered by the nucleoprotein on the inside, the envelope and matrix proteins within the membrane, and the spike protein on the surface of the virus. b, The structure of the spike protein; one monomer is highlighted in dark brown and the RBD is shown in red. cl, Current SARS-CoV-2 vaccine candidates include inactivated virus vaccines (c), live attenuated vaccines (d), recombinant protein vaccines based on the spike protein (e), the RBD (f) or on virus-like particles (g), replication-incompetent vector vaccines (h), replication-competent vector vaccines (i), inactivated virus vector vaccines that display the spike protein on their surface (j), DNA vaccines (k) and RNA vaccines (l).

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