Traditional vaccine development can take 15 years or more, starting with a lengthy discovery phase in which vaccines are designed and exploratory preclinical experiments are conducted. This is usually followed by a phase in which more formal preclinical experiments and toxicology studies are performed and in which production processes are developed. During this process an investigational new drug (IND) application is filed and the vaccine candidate then enters phase I, II and III trials. If, when phase III trials are completed, the predetermined end points have been met, a biologics licence application (BLA) is filed, reviewed by regulatory agencies and finally the vaccine is licensed. After that point, large-scale production begins. Vaccine development for SARS-CoV-2 is following an accelerated timeline. Because of knowledge gained from the initial development of vaccines for SARS-CoV and MERS-CoV, the discovery phase was omitted. Existing processes were adopted, and phase I/II trials were started. Phase III trials were initiated after the interim analysis of phase I/II results, with several clinical trial stages running in parallel. In the meantime, vaccine producers have started the large-scale production of several vaccine candidates, at risk. The exact pathway by which these vaccine candidates will be licensed—for example, through an initial emergency use authorization—is not yet clear.