Extended Data Fig. 3: Comparison of the structural cell transcriptomes to published reference data. | Nature

Extended Data Fig. 3: Comparison of the structural cell transcriptomes to published reference data.

From: Structural cells are key regulators of organ-specific immune responses

Extended Data Fig. 3

a, Overlap of the identified cell-type-specific and organ-specific marker genes (derived from the RNA-seq experiments in the current study) with tissue-specific gene sets from a microarray-based expression atlas (two-sided Fisher’s exact test with multiple-testing correction). b, Gene expression across cell types and organs (from the current study) aggregated across marker genes of structural cell clusters in a single-cell RNA-seq atlas of the mouse19. c, Gene expression across cell types and organs (from the current study) plotted for a manually curated list of commonly used markers of structural cells. d, Hierarchical clustering of structural cells across cell types and organs based on the transcriptome profiles from the current study. Sample size (all panels): n = 3 independent biological replicates.

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