Extended Data Fig. 7: Detection and analysis of genes with unrealized epigenetic potential. | Nature

Extended Data Fig. 7: Detection and analysis of genes with unrealized epigenetic potential.

From: Structural cells are key regulators of organ-specific immune responses

Extended Data Fig. 7

a, Scatterplot showing the correlation between chromatin accessibility in promoter regions and the corresponding gene expression levels in structural cells across cell types and organs. Genes with significant unrealized epigenetic potential (calculated as the difference between normalized ATAC-seq and RNA-seq signals) are highlighted in blue. b, Enrichment of immune-related gene sets among the genes with unrealized epigenetic potential (two-sided Fisher’s exact test with multiple-testing correction). Sample size (all panels): n = 2 independent biological replicates.

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